Rui Vitória has named a 21-man preliminary squad for the visit of Borussia Dortmund. Jonas has been included, but is a major doubt after missing training on Monday with neck pain. Andrija Živković serves a one-game suspension carried over from his time at Partizan Belgrade.
Lisandro López is still absent after colliding with the post against Moreirense in January. Álex Grimaldo has been removed from Benfica's European roster as he continues his rehabilitation from abdominal surgery.
Eduardo Salvio has recovered from his ankle injury, and January signing Pedro Pereira is included for the first time. If selected, Luisão will make his 500th competitive appearance for the club.
Tuesday's game at the Estádio da Luz begins at 19:45 local time, and will be officiated by Italian referee Nicola Rizzoli.
Goalkeepers: Ederson and Júlio César
Defenders: Luisão, Lindelöf, Jardel, André Almeida, Nélson Semedo, Eliseu and Pedro Pereira
Midfielders: Fejsa, Samaris, Filipe Augusto, André Horta, Carrillo, Pizzi, Salvio, Cervi and Rafa Silva
Forwards: Raúl, Jonas and Mitroglou