Benfica will travel to Madeira without a natural left-back in their squad. Álex Grimaldo is still struggling with an abdominal problem, while Eliseu picked up a thigh strain in the win over Moreirense. André Almeida is expected to play the role in their absence.
André Horta (thigh) and Jonas (foot) remain sidelined, while Danilo has been overlooked.
The match at the newly-renovated Estádio dos Barreiros gets underway at 20:30 on Friday.
Goalkeepers: Ederson, Júlio César and Paulo Lopes
Defenders: Lisandro, Luisão, Lindelof, Jardel, André Almeida and Nélson Semedo
Midfielders: Fejsa, Samaris, Carrillo, Živković, Salvio, Pizzi, Cervi, Celis and Rafa Silva
Forwards: Raúl, Mitroglou and Gonçalo Guedes